Glutaric Aciduria Type I

Glutaric Aciduria Type I is a rare inherited metabolic disease caused by enzyme deficiency. People diagnosed with glutaric aciduria are unable to break down the amino acids lysine, hydroxylysine and tryptophan. It can cause neurological damage, particularly affecting movement and speech. It consequently can lead to severe disability or even death. The basis of therapy is a diet limiting amino acids whose metabolism is damaged, i.e. lysine and tryptophan. They may need extra supplementation, based on glucose polymer powders during acute illness. This may be delivered via a feeding tube. Additionally, supplementation with high doses of carnitine is necessary. People diagnosed with Glutaric Aciduria Type I therefore must carry on board and/or checked luggage:

• Special protein substitute formulas and/or vitamins (liquid, powder or pills)
• Glucose polymer powders
• Low protein foods
• Pharmaceutical products dedicated to Glutaric Aciduria type I treatment

Please be advised that a person with Glutaric Aciduria Type I may need medical equipment such as wheelchairs, feeding tubes and pumps with severe disability or for acute illness.